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Clinical decision support tool. Does not replace professional veterinary judgment. Always verify recommendations with current references.
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| Condition | Prevalence | Onset | Severity | Screening |
|---|---|---|---|---|
| Fucosidosis (FUCA1) | Autosomal recessive; genetic test available | 18 months-4 years | LIFE THREATENING | FUCA1 genetic test. Progressive ataxia, behaviour change and weight loss in a young adult Springer is the presenting picture; the disease is fatal and untreatable. |
| Immune-Mediated Hemolytic Anemia | Over-represented | 2-8 years | LIFE THREATENING | CBC with slide agglutination and a blood smear for any pale, lethargic or icteric Springer — same day, not "recheck in a week". |
| Phosphofructokinase (PFK) Deficiency | Autosomal recessive; genetic test available | Congenital — episodic crises from puppyhood | SEVERE | PFKM genetic test before breeding or field work. Suspect it in a Springer with episodic pigmenturia, pallor and fever after excitement or exercise. |
| Progressive Retinal Atrophy (cord1 / RPGRIP1) | Elevated; genetic test available | 2-6 years (variable expression) | SEVERE | RPGRIP1 genetic test plus annual CAER exam. |
| Hip Dysplasia | Elevated | 1-2 years | MODERATE RISK | OFA or PennHIP evaluation by age 2. |
| Chronic Otitis Externa | Very common — pendulous ears and ceruminous glands | 1 year onward | MODERATE RISK | Otoscopic exam every visit; cytology before each treatment course. |
Genotype or confirm PFK status before elective anesthesia. In an affected or untested dog, avoid respiratory alkalosis: ventilate to normocapnia (ETCO2 35-45 mmHg), never hyperventilate, and minimise pre-operative excitement and struggling. Maintain normothermia, keep well hydrated, and check PCV and urine colour post-operatively — pigmenturia is the first sign of a crisis.