Dr. Rosie DVM

Clinical decision support tool. Does not replace professional veterinary judgment. Always verify recommendations with current references.

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Clinical decision support tool. Does not replace professional veterinary judgment. Always verify recommendations with current references.

Whippet

DOG· MEDIUM· Lifespan: 12-15 years

🧬 Genetic Drug Sensitivities

🔴 CYP2B11 (Reduced hepatic metabolism)

Prevalence: Unknown

Sighthound anesthetic sensitivity. Low body fat and reduced CYP2B11 activity. Reduce induction dose by 25-50%.

REDUCE DOSEPropofol

🏥 Anesthesia Considerations

⚠ Sighthound Anesthetic Sensitivity

Low body fat → prolonged recovery from lipid-soluble agents (thiopental, propofol). Reduce induction doses 25-50%. Use lean-body-mass dosing. CYP2B11 deficiency in Greyhounds = slow barbiturate/propofol metabolism. Prefer alfaxalone for induction. Extended post-anesthetic monitoring required.